Hyaluronans or Hyaluricacid
Hyaluronans or
Hyaluricacid
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Hyaluronan
References[edit]
Hyaluronan กำลังได้รับความนิยมในการวิจัยวิศวกรรมเนื้อเยื่อ.
[76] [77] โดยเฉพาะอย่างยิ่งจำนวนของกลุ่มวิจัยได้พบคุณสมบัติ Hyaluronan
สำหรับวิศวกรรมเนื้อเยื่อ ,
เนื่องจากความสามารถในการควบคุมการเจเนซิสโดยการกระตุ้นเซลล์บุผนังหลอดเลือด เพิ่มจำนวนกรดไฮยาลูโรสามารถใช้ในการสร้างไฮโดรเจลในหลอดเลือด. [82] ไฮโดรเจลเหล่านี้มีคุณสมบัติคล้ายกับเนื้อเยื่ออ่อนมนุษย์
และควบคุมได้ง่าย เสริมการขยายตัวและการสร้างเครือข่ายหลอดเลือด การผลิตไฮโดรเจล คุณสมบัตินี้ ทำให้มีการนำไปใช้รักษาโรคข้อเข่าเสื่อมผ่านการฉีดเข้าไปในข้อต่อ แม่ว่าจะไม่ได้รับการพิสูจน์
แต่จะสร้างผลประโยชน์อย่างมีนัยสำคัญ และอาจมีผลกระทบอย่างรุนแรงที่อาจเกิดขึ้น. [8] อาการผิวหนังแห้งเป็นสะเก็ด
(xerosis) เช่นที่เกิดจากโรคผิวหนังภูมิแพ้ (กลาก) อาจจะรักษาได้ด้วยโลชั่นบำรุงผิวที่มีส่วนผสมของยาโซเดียม Hyaluronate
ใช้รักษามะเร็งต่อมลูกหมากและมะเร็งเต้านม ใช้หลังผ่าตัดเพื่อการรักษาเนื้อเยื่อโดยเฉพาะอย่างยิ่งหลังการผ่าตัดต้อกระจก.
[12] รักษาแผล
ควบคุมเม็ดเลือดขาวให้เกิดภูมิคุ้มกัน ใช้ฉีดเพื่อรักษาริ้วรอยเหี่ยวย่น
แต่มีผลคือรอยพกช้ำ และมีการปรับปรุงเทคนิคดังกล่าวให้เกิดรอยพกช้ำน้อยลงได้
ในปี 2007
ได้รับการรับรองให้เป็นยารักษาโรคเข่าข้อเสื่อม
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Hyaluronans or
Hyaluricacid
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Identifiers
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Properties
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(C14H21NO11)n
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soluble (sodium salt)
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Hazards
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> 2400 mg/kg (mouse, oral, sodium
salt)
>4000 mg/kg (mouse, subcutaneous, sodium salt) 1500 mg/kg (mouse, intraperitoneal, sodium salt)[1] |
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Related compounds
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Related compounds
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Except where noted otherwise, data
are given for materials in their standard state (at 25 °C
(77 °F), 100 kPa)
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/
?)
Hyaluronan (also called hyaluronic acid or hyaluronate or HA)
References[edit]
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